{"id":6231,"date":"2025-01-09T15:00:30","date_gmt":"2025-01-09T07:00:30","guid":{"rendered":"https:\/\/www.csclinic.com.tw\/?p=6231"},"modified":"2025-11-28T11:12:55","modified_gmt":"2025-11-28T03:12:55","slug":"%e5%88%b7%e7%89%99%e4%b8%8d%e5%be%b9%e5%ba%95%ef%bc%8c%e7%ab%9f%e6%9c%83%e8%ae%93%e5%bf%83%e8%87%9f%e5%92%8c%e5%a4%a7%e8%85%a6%e4%bb%98%e5%87%ba%e6%b2%89%e9%87%8d%e4%bb%a3%e5%83%b9","status":"publish","type":"post","link":"https:\/\/www.csclinic.com.tw\/%e5%88%b7%e7%89%99%e4%b8%8d%e5%be%b9%e5%ba%95%ef%bc%8c%e7%ab%9f%e6%9c%83%e8%ae%93%e5%bf%83%e8%87%9f%e5%92%8c%e5%a4%a7%e8%85%a6%e4%bb%98%e5%87%ba%e6%b2%89%e9%87%8d%e4%bb%a3%e5%83%b9\/","title":{"rendered":"\u5237\u7259\u4e0d\u5fb9\u5e95\uff0c\u7adf\u6703\u8b93\u5fc3\u81df\u548c\u5927\u8166\u4ed8\u51fa\u6c89\u91cd\u4ee3\u50f9"},"content":{"rendered":"

\"\"<\/h2>\n

\u4e00\u3001\u5237\u7259\u8207\u5168\u8eab\u5065\u5eb7\u7684\u95dc\u806f<\/strong><\/h2>\n

\u5b88\u8b77\u53e3\u8154\u5c31\u662f\u5b88\u8b77\u5fc3\u8166\uff0c\u5728\u4e9e\u6d32\u5237\u7259\u7684\u6b77\u53f2\u53ef\u8ffd\u6eaf\u81f3\u53e4\u4ee3\u4e2d\u570b\u548c\u5370\u5ea6\u3002\u4e2d\u570b\u65e9\u5728\u5546\u4ee3\uff08\u7d04\u516c\u5143\u524d1600 \u5e74\uff09\u5c31\u4f7f\u7528\u300c\u694a\u679d\u300d\u6e05\u6f54\u7259\u9f52\uff0c\u53d6\u81ea\u9999\u6728\u7684\u7d30\u679d\u5177\u6709\u5929\u7136\u6297\u83cc\u6548\u679c\u3002\u5230\u4e86\u5510\u4ee3\uff08\u516c\u51437\u4e16\u7d00\uff09\uff0c\u4e2d\u570b\u767c\u660e\u4e86\u6700\u65e9\u7684\u5237\u72c0\u7259\u5177\uff0c\u7528\u8c6c\u9b03\u4f5c\u70ba\u5237\u6bdb\uff0c\u56fa\u5b9a\u5728\u7af9\u67c4\u4e0a\uff0c\u662f\u73fe\u4ee3\u7259\u5237\u7684\u96db\u5f62\u3002\u800c\u5728\u5370\u5ea6\uff0c\u53e4\u4ee3\u4f7f\u7528\u690d\u7269\u679d\u689d\u5982\u300c\u5370\u5ea6\u82e6\u695d\u6a39\u6a39\u679d\u300d\u4f86\u6e05\u6f54\u7259\u9f52\uff0c\u5176\u6297\u83cc\u7279\u6027\u81f3\u4eca\u4ecd\u70ba\u90e8\u5206\u5730\u5340\u6240\u7528\u3002\u9019\u4e9b\u667a\u6167\u53cd\u6620\u4e86\u4e9e\u6d32\u53e4\u4ee3\u5c0d\u53e3\u8154\u5065\u5eb7\u7684\u91cd\u8996\u3002\u53e3\u8154\u5065\u5eb7\u4e0d\u50c5\u95dc\u4e4e\u7259\u9f52\u8207\u7259\u5468\u7d44\u7e54\uff0c\u9084\u8207\u5168\u8eab\u5065\u5eb7\u5bc6\u5207\u76f8\u95dc\u3002\u8d8a\u4f86\u8d8a\u591a\u7684\u7814\u7a76\u8b49\u5be6\uff0c\u53e3\u8154\u6e05\u6f54\u4e0d\u8db3\u53ef\u80fd\u6210\u70ba\u5f15\u767c\u591a\u7a2e\u5168\u8eab\u6027\u75be\u75c5\u7684\u98a8\u96aa\u56e0\u5b50\uff0c\u5305\u62ec\u5fc3\u81df\u75c5\u3001\u4e2d\u98a8\u4ee5\u53ca\u795e\u7d93\u9000\u884c\u6027\u75be\u75c5\u5982\u963f\u8332\u6d77\u9ed8\u75c7\u7b49\u3002\u9019\u4e9b\u767c\u73fe\u986f\u793a\uff0c\u65e5\u5e38\u751f\u6d3b\u4e2d\u770b\u4f3c\u5fae\u4e0d\u8db3\u9053\u7684\u5237\u7259\u7fd2\u6163\uff0c\u5be6\u969b\u4e0a\u5c0d\u5fc3\u81df\u548c\u5927\u8166\u7684\u5065\u5eb7\u6709\u8457\u6df1\u9060\u7684\u5f71\u97ff\u3002<\/p>\n

<\/h2>\n

\u4e8c\u3001\u53e3\u8154\u8207\u5168\u8eab\u5065\u5eb7\u7684\u6f5b\u5728\u554f\u984c<\/strong><\/h2>\n

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<\/h2>\n

\"\"<\/p>\n

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\u611f\u67d3\u6027\u5fc3\u5167\u819c\u708e\uff08Infective Endocarditis, IE\uff09\u662f\u4e00\u7a2e\u7531\u7d30\u83cc\u3001\u771f\u83cc\u6216\u5176\u4ed6\u5fae\u751f\u7269\u611f\u67d3\u5fc3\u81df\u5167\u819c\u6216\u74e3\u819c\u7d44\u7e54\u6240\u5f15\u8d77\u7684\u75be\u75c5\uff0c\u53ef\u80fd\u5c0e\u81f4\u56b4\u91cd\u7684\u5fc3\u8840\u7ba1\u5f8c\u679c\u3002\u53e3\u8154\u4e2d\u7684\u7d30\u83cc\u662f\u611f\u67d3\u6027\u5fc3\u5167\u819c\u708e\u7684\u91cd\u8981\u4f86\u6e90\u4e4b\u4e00\uff0c\u5c24\u5176\u662f\u5728\u53e3\u8154\u885b\u751f\u4e0d\u826f\u6216\u9032\u884c\u7259\u79d1\u6cbb\u7642\u5f8c\u3002<\/p>\n

1. \u7259\u5468\u75c5\u548c\u83cc\u8840\u75c7\u7684\u95dc\u806f<\/strong><\/span>
\n\u7259\u5468\u75c5\u662f\u4e00\u7a2e\u6162\u6027\u708e\u75c7\u6027\u75be\u75c5\uff0c\u7531\u75c5\u539f\u83cc\uff08\u5982\u7259\u9f66\u535f\u5549\u55ae\u80de\u83ccPorphyromonas gingivalis \u548c\u5177\u6838\u68ad\u687f\u83cc Fusobacteriumnucleatum\uff09\u5f15\u8d77\uff0c\u6703\u7834\u58de\u7259\u9f66\u5c4f\u969c\uff0c\u589e\u52a0\u7d30\u83cc\u9032\u5165\u8840\u6db2\u5faa\u74b0\u7684\u98a8\u96aa\u3002
\n\u83cc\u8840\u75c7\uff08Bacteremia\uff09\u6307\u7d30\u83cc\u66ab\u6642\u9032\u5165\u8840\u6db2\u7cfb\u7d71\u7684\u60c5\u6cc1\uff0c\u53ef\u80fd\u767c\u751f\u5728\u65e5\u5e38\u751f\u6d3b\u4e2d\uff08\u5982\u5237\u7259\u3001\u7259\u7dda\u6e05\u6f54\uff09\u6216\u4fb5\u5165\u6027\u7259\u79d1\u64cd\u4f5c\uff08\u5982\u62d4\u7259\u3001\u7259\u5468\u624b\u8853\uff09\u5f8c\u3002<\/p>\n

2. \u7d30\u83cc\u5728\u5fc3\u81df\u5167\u819c\u7684\u9644\u8457\u8207\u611f\u67d3<\/strong><\/span>
\n\u7576\u7d30\u83cc\u9032\u5165\u8840\u6db2\u5f8c\uff0c\u53ef\u80fd\u5728\u4ee5\u4e0b\u60c5\u6cc1\u4e0b\u9644\u8457\u65bc\u5fc3\u81df\u5167\u819c\u6216\u74e3\u819c\uff1a
\n\u25aa \u5fc3\u81df\u74e3\u819c\u5df2\u6709\u640d\u50b7\u6216\u7570\u5e38\uff08\u5982\u74e3\u819c\u9223\u5316\u3001\u4eba\u5de5\u74e3\u819c\u3001\u98a8\u6fd5\u6027\u5fc3\u81df\u75c5\uff09\u3002
\n\u25aa \u8840\u6db2\u6d41\u52d5\u7570\u5e38\uff08\u5982\u5148\u5929\u6027\u5fc3\u81df\u75c5\uff09\u9020\u6210\u5fc3\u5167\u819c\u7684\u5fae\u5275\u50b7\u3002
\n\u7d30\u83cc\u901a\u904e\u8868\u9762\u7c98\u9644\u86cb\u767d\uff08\u5982\u7259\u5468\u81f4\u75c5\u83cc\u8868\u9762\u7684 FimA \u86cb\u767d\uff09\u9ecf\u9644\u5728\u74e3\u819c\u7d44\u7e54\uff0c\u4e26\u5728\u5c40\u90e8\u5f62\u6210\u83cc\u6591\uff0c\u9032\u4e00\u6b65\u767c\u5c55\u70ba\u5fc3\u5167\u819c\u708e\u75c5\u7076\u3002<\/p>\n

3. \u708e\u75c7\u548c\u514d\u75ab\u53cd\u61c9<\/span><\/strong>
\n\u7d30\u83cc\u9644\u8457\u5f8c\u6703\u523a\u6fc0\u5c40\u90e8\u514d\u75ab\u53cd\u61c9\uff0c\u5f15\u767c\u6162\u6027\u708e\u75c7\uff0c\u9032\u4e00\u6b65\u640d\u50b7\u74e3\u819c\u7d44\u7e54\u3002\u7d30\u83cc\u9084\u6703\u5206\u6ccc\u6bd2\u7d20\uff08\u5982\u8102\u591a\u91a3\uff0cLPS\uff09\u52a0\u5287\u7d44\u7e54\u640d\u50b7\u3002\u611f\u67d3\u90e8\u4f4d\u7684\u7d30\u83cc\u6703\u6301\u7e8c\u91cb\u653e\u5230\u8840\u6db2\u4e2d\uff0c\u53ef\u80fd\u5f15\u767c\u6557\u8840\u75c7\u6216\u591a\u5668\u5b98\u529f\u80fd\u640d\u50b7\u3002<\/p>\n

\"\"<\/h2>\n

\u56db\u3001\u63d0\u5347\u53e3\u8154\u5065\u5eb7\u7684\u6b63\u78ba\u5237\u7259\u7b56\u7565<\/strong><\/h2>\n

\u70ba\u4e86\u964d\u4f4e\u53e3\u8154\u76f8\u95dc\u75be\u75c5\u5c0d\u5168\u8eab\u5065\u5eb7\u7684\u5f71\u97ff\uff0c\u638c\u63e1\u6b63\u78ba\u7684\u5237\u7259\u65b9\u6cd5\u81f3\u95dc\u91cd\u8981\u3002\u4ee5\u4e0b\u662f\u5177\u9ad4\u7684\u4e09\u500b\u6b65\u9a5f\u548c\u76f8\u95dc\u5efa\u8b70\uff0c\u5e6b\u52a9\u5fb9\u5e95\u6e05\u6f54\u53e3\u8154\uff0c\u6709\u6548\u6e1b\u5c11\u7d30\u83cc\u8ca0\u64d4\uff1a
\n1. \u5237\u7259\u6642\u9593\u5920\uff0c\u6280\u8853\u6b63\u78ba<\/strong><\/span>
\n\u2022 \u6642\u9593\u5efa\u8b70\uff1a\u6bcf\u6b21\u5237\u7259\u4fdd\u6301 2\u5206\u9418\uff0c\u5c07\u53e3\u8154\u5206\u70ba\u56db\u500b\u5340\u57df\uff08\u4e0a\u5de6\u3001\u4e0a\u53f3\u3001\u4e0b\u5de6\u3001\u4e0b\u53f3\uff09\uff0c\u6bcf\u500b\u5340\u57df\u61c9\u81f3\u5c11\u82b1\u8cbb30\u79d2\u3002
\n\u2022 \u5de5\u5177\u9078\u64c7\uff1a\u9078\u64c7 \u8edf\u6bdb\u7259\u5237\uff0c\u4ee5\u6e1b\u5c11\u5c0d\u7259\u9f66\u548c\u743a\u746f\u8cea\u7684\u640d\u50b7\uff0c\u4e26\u642d\u914d\u542b\u6c1f\u7259\u818f\u4f7f\u7528\u3002
\n\u2022 \u6280\u8853\u91cd\u9ede\uff1a\u4f7f\u7528\u5713\u5f27\u5237\u7259\u6cd5\uff08Bass\u5237\u7259\u6cd5\uff09\uff0c\u5c07\u5237\u6bdb\u8207\u7259\u9f66\u5448 45\u5ea6\u89d2\uff0c\u8f15\u8f15\u5237\u52d5\u7259\u9f66\u908a\u7de3\u548c\u7259\u9f52\u8868\u9762\uff0c\u907f\u514d\u904e\u5ea6\u7528\u529b\u4ee5\u9632\u7259\u9f66\u840e\u7e2e\u6216\u743a\u746f\u8cea\u78e8\u640d\u3002<\/p>\n

2. \u7259\u7e2b\u6e05\u6f54\u5fc5\u4e0d\u53ef\u5c11<\/strong><\/span>
\n\u2022 \u7259\u7dda\u4f7f\u7528\uff1a\u6bcf\u5929\u81f3\u5c11\u4e00\u6b21\u4f7f\u7528\u7259\u7dda\uff0c\u5c07\u7259\u7dda\u8f15\u8f15\u6ed1\u5165\u7259\u7e2b\uff0c\u5f62\u6210\u201cC\u201d\u5f62\u8cbc\u5408\u7259\u9f52\u8868\u9762\uff0c\u6e05\u9664\u7259\u7e2b\u9593\u7684\u6b98\u7559\u7269\u8207\u7259\u83cc\u6591\u3002
\n\u2022 \u7259\u9593\u5237\u9078\u64c7\uff1a\u7259\u7e2b\u8f03\u5927\u7684\u6210\u5e74\u4eba\uff0c\u61c9\u6839\u64da\u7259\u9593\u5927\u5c0f\u9078\u64c7\u9069\u5408\u7684\u7259\u9593\u5237\uff0c\u5c07\u5176\u8f15\u8f15\u63d2\u5165\u7259\u7e2b\uff0c\u524d\u5f8c\u79fb\u52d5\u6e05\u9664\u7259\u83cc\u6591\u3002
\n\u2022 \u79d1\u5b78\u4f9d\u64da\uff1a\u7814\u7a76\u986f\u793a\uff0c\u7259\u7dda\u548c\u7259\u9593\u5237\u53ef\u964d\u4f4e\u7259\u5468\u75c5\u98a8\u96aa\u9054 40%\uff0c\u6709\u6548\u6e1b\u5c11\u7d30\u83cc\u901a\u904e\u8840\u6db2\u50b3\u64ad\u7684\u53ef\u80fd\u6027\u3002<\/p>\n

3. \u5225\u5ffd\u7565\u820c\u982d\u6e05\u6f54<\/span><\/strong>
\n\u2022 \u65b9\u6cd5\u5efa\u8b70\uff1a\u5728\u5237\u7259\u5f8c\u4f7f\u7528 \u5c08\u7528\u820c\u82d4\u5237 \u6216\u7259\u5237\u8f15\u8f15\u5237\u62ed\u820c\u982d\u8868\u9762\uff0c\u6bcf\u6b21\u5f9e\u820c\u6839\u5411\u820c\u5c16\u8f15\u522e\u6578\u6b21\uff0c\u4ee5\u6e05\u9664\u9644\u8457\u7684\u7d30\u83cc\u548c\u98df\u7269\u6b98\u6e23\u3002
\n\u2022 \u6548\u679c\u91cd\u9ede\uff1a\u9810\u9632\u53e3\u81ed\uff0c\u4e26\u6e1b\u5c11\u53e3\u8154\u7d30\u83cc\u7e3d\u91cf\uff0c\u63d0\u5347\u6574\u9ad4\u53e3\u8154\u885b\u751f\u6c34\u5e73\u3002<\/p>\n

\u4e94\u3001\u5177\u9ad4\u7684\u6bcf\u65e5\u53e3\u8154\u8b77\u7406:
\n1. \u65e9\u6668\uff1a\u8d77\u5e8a\u5f8c\u7528\u6eab\u6c34\u6f31\u53e3\uff0c\u4f7f\u7528\u542b\u6c1f\u7259\u818f\u5237\u72592\u5206\u9418\uff0c\u63a5\u8457\u4f7f\u7528\u7259\u7dda\u6e05\u6f54\u7259\u7e2b\uff0c\u518d\u8f15\u5237\u820c\u82d4\u4ee5\u6e05\u65b0\u53e3\u6c23\u3002
\n2. \u767d\u5929\uff1a\u9032\u9910\u5f8c\u53ef\u4f7f\u7528\u6e05\u6c34\u6f31\u53e3\u6216\u7121\u7cd6\u53e3\u9999\u7cd6\u6e05\u6f54\u7259\u9f52\uff0c\u907f\u514d\u6b98\u6e23\u6eef\u7559\u3002
\n3. \u591c\u665a\uff1a\u7761\u524d\u91cd\u8907\u65e9\u6668\u7684\u5237\u7259\u7a0b\u5e8f\uff0c\u78ba\u4fdd\u5fb9\u5e95\u6e05\u6f54\u7259\u9f52\u8868\u9762\u8207\u7259\u7e2b\uff0c\u4e26\u642d\u914d\u542b\u6297\u83cc\u6210\u5206\u7684\u6f31\u53e3\u6c34\u63d0\u5347\u53e3\u8154\u6e05\u6f54\u6548\u679c\u3002<\/p>\n

 <\/p>\n

\u7acb\u5373\u8aee\u8a62<\/a><\/p>\n

 <\/p>\n

\u516d\u3001\u7d50\u8ad6
\n\u53e3\u8154\u5065\u5eb7\u662f\u5f88\u91cd\u8981\u7684\uff0c\u4e5f\u8207\u5927\u5bb6\u65e5\u5e38\u751f\u6d3b\u4e2d\u606f\u606f\u76f8\u95dc\uff0c\u901a\u904e\u6bcf\u5929\u6295\u5165\u6578\u5206\u9418\u9032\u884c\u79d1\u5b78\u3001\u5fb9\u5e95\u7684\u53e3\u8154\u6e05\u6f54\uff0c\u4e0d\u50c5\u80fd\u7dad\u8b77\u7259\u9f52\u548c\u7259\u5468\u7d44\u7e54\u7684\u5065\u5eb7\uff0c\u9084\u80fd\u964d\u4f4e\u5168\u8eab\u6027\u767c\u708e\u8207\u591a\u7a2e\u75be\u75c5\u7684\u98a8\u96aa\uff0c\u5f9e\u6839\u672c\u990a\u6210\u597d\u7fd2\u6163\uff0c\u4fc3\u9032\u66f4\u7f8e\u597d\u7684\u5065\u5eb7\u751f\u6d3b\u3002<\/p>\n

 <\/p>\n

\u4e03\u3001\u6587\u737b\u4f86\u6e90:
\n1.Tonetti, M. S., Jepsen, S., Jin, L., & Otomo-Corgel, J. (2013).Impact of the global burden of periodontal diseases on health,nutrition, and well-being of mankind: A call for global action.Journal of Clinical Periodontology, 40(Suppl. 14), S1\u2013S7.https:\/\/doi.org\/10.1111\/jcpe.12061
\n2.Dominy, S. S., Lynch, C., Ermini, F., Benedyk, M., Marczyk, A.,Konradi, A., Nguyen, M., & Monack, D. (2019). Porphyromonasgingivalis in Alzheimer\u2019s disease brains: Evidence for diseasecausation and treatment with small-molecule inhibitors. ScienceAdvances, 5(1), eaau3333. https:\/\/doi.org\/10.1126\/sciadv.aau3333
\n3.Hajishengallis, G. (2014). Immunomicrobial pathogenesis of periodontitis: Keystones, pathobionts, and host response. Trends inImmunology, 35(1), 3-11. https:\/\/doi.org\/10.1016\/j.it.2013.09.001
\n4.Cahill, T. J., Harrison, J. L., Jewell, P., Onakpoya, I., Chambers, J. B., Dayer, M., & Lockhart, P. B. (2017). Antibiotic prophylaxisfor infective endocarditis: A systematic review and meta-analysis. Heart, 103(12), 937-944. https:\/\/doi.org\/10.1136\/heartjnl-2016-310925<\/p>\n","protected":false},"excerpt":{"rendered":"

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